英文名称： Anti-RB1(Phospho-Ser608) rabbit polyclonal antibody
别 名： RB; pRb; OSRC; pp110; p105-Rb; PPP1R130
相关类别： 一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： RB1(Phospho-Ser608)
反应种属： Human Mouse
标 记 物： Unconjugate
克隆类型： Unconjugate
技术规格
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Background: |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
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Applications: |
WB, IHC |
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Name of antibody: |
RB1(Phospho-Ser608) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 608(Y-L-S(p)-P-V) derived from Human Retinoblastoma. |
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Full name: |
retinoblastoma 1 |
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Synonyms： |
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130 |
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SwissProt: |
P06400 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
106 kDa |
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WB Positive control: |
Jurkat cells lysates |
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WB Recommended dilution: |
500-1000 |
