英文名称： Anti-RASGEF1A rabbit polyclonal antibody
别 名： CG4853
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： RASGEF1A
反应种属： Human
标记物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
RASGEF1A |
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Immunogen: |
Fusion protein of human RASGEF1A |
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Full name: |
RasGEF domain family, member 1A |
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Synonyms： |
CG4853 |
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SwissProt: |
Q8N9B8 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human breast cancer and human thyroid cancer |
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IHC Recommend dilution: |
20-100 |
