英文名称： Anti-RAD50 rabbit polyclonal antibody
别 名： NBSLD, RAD502, hRad50
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： RAD50
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
RAD50 |
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Immunogen: |
Synthetic peptide of human RAD50 |
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Full name: |
RAD50 double strand break repair protein |
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Synonyms: |
NBSLD; RAD502; hRad50 |
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SwissProt: |
Q92878 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human colon cancer and Human gastric cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
154 kDa |
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WB Positive control: |
293T, Hela, K562, NIH/3T3 and RAW264.7 cells |
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WB Recommended dilution: |
500-2000 |
