英文名称： Anti-PTPRK rabbit polyclonal antibody
别 名： R-PTP-kappa
抗 原： PTPRK
储 存： 冷冻（-20℃）
宿 主： Rabbit
相关类别： 一抗
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PTPRK |
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Immunogen: |
Fusion protein of human PTPRK |
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Full name: |
protein tyrosine phosphatase, receptor type, K |
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Synonyms： |
R-PTP-kappa |
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SwissProt: |
Q6P493 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human liver cancer and Human ovarian cancer |
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IHC Recommend dilution: |
25-100 |
