英文名称： Anti-HBG1/HBG2 rabbit polyclonal antibody
别 名： hemoglobin subunit gamma 1/2; fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： HBG1/HBG2
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into hood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
HBG1/HBG2 |
|
Immunogen: |
Fusion protein of human HBG1/HBG2 |
|
Full name: |
hemoglobin subunit gamma 1/2 |
|
Synonyms: |
fetal hemoglobin; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979; TNCY; HBG-T1 |
|
SwissProt: |
P69891/P69892 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human thyroid cancer |
|
IHC Recommend dilution: |
40-200 |
|
WB Predicted band size: |
16 kDa |
|
WB Positive control: |
Human plasma solution |
|
WB Recommended dilution: |
500-2000 |
